Gleason Score

A Gleason Score is a grading system that defines the aggressiveness of the prostate cancer. When cancer is suspected, several biospies are taken of the prostate. The tissue samples are then compared to a standard of five tissue grades that were established by Dr. Donald F. Gleason. The pathologist determines how much of the cancerous tissue is of which grade. A Gleason Score is a combination of two Gleason grades. The predominant tissue (51% or more) determines the first number. The second number is determined by the secondary grade and must make up more than 5% but less than 50% of the sample. The two numbers are then added to determine the Gleason Score. For example, cancer tissue that is predominantly grade 3 and secondarily grade 4 gives a Gleason Score of 7 (3+4). It is important to note that a Gleason Score of 7 (4+3) is significantly different from a Gleason Score of 7 (3+4) and may require different treatment.

For more information see: PSA Rising


Close
E-mail It