Measles Virus May Treat Prostate Cancer

A friend with prostate cancer sent this to me, I thought others might be interested also. I will look for more information to post later.

Researchers at the Mayo Clinic have found that certain strains of the measles virus, including one known as MV-CEA, may be an effective treatment for advanced prostate cancer. The type of treatment, known as virotherapy, can infect and kill prostate cancer cells.Prostate cancer is the second most common cancer-related cause of death in American men, accounting for almost 29,000 fatalities each year. Up to 34 percent of the 186,000 men diagnosed each year will eventually suffer a relapse, and there are no curative therapies available for locally advanced or metastatic prostate cancer.Mice treated with the MV-CEA lived twice as long as the controls and one-fifth of the treated animals had complete tumor regression.Since primary tumor sites in prostate cancer are easily accessible, the virotherapy agent can be applied directly to the prostate tumor using ultrasound. The CEA marker (carcinoembryonic antigen, produced when the virus multiples) can be monitored by a simple blood test, allowing accurate monitoring and individualized treatment.“Based on our preclinical results as well as the safety of measles derivatives in clinical trials against other tumor types, these viral strains could represent excellent candidates for clinical testing against advanced prostate cancer, including androgen resistant tumors,” says Evanthia Galanis, M.D., of the Mayo Clinic. 

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